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相关概念视频

Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

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The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
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What is the Immune System?01:38

What is the Immune System?

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Overview
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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

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Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
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Development of Immunocompetence01:22

Development of Immunocompetence

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

1.7K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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相关实验视频

Updated: Jan 11, 2026

A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses
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关于口腔免疫的介绍

Heliya Ziaei1, Nima Rezaei2,3,4,5

  • 1Universal Scientific Education and Research Network (USERN), Los Angeles, CA, USA.

Advances in experimental medicine and biology
|November 12, 2025
PubMed
概括

口腔免疫系统平衡耐受性和防御性,对于防止病原体进入和保持健康至关重要. 干扰可以导致局部和全身疾病,突出了针对性治疗的必要性.

关键词:
口服免疫力 口服免疫力口服免疫学 口服免疫学口腔炎症是一种口腔炎症.

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Last Updated: Jan 11, 2026

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科学领域:

  • 免疫学 免疫学 免疫学
  • 口腔生物学 口腔生物学
  • 微生物组研究 微生物组研究

背景情况:

  • 口腔拥有复杂的免疫系统,包括上皮屏障,唾液因子和居住免疫细胞.
  • 这个系统保持对共生微生物和饮食抗原的耐受性,同时防御病原体.
  • 口腔免疫的失调有助于局部炎症和全身性疾病.

研究的目的:

  • 提供口腔免疫成分及其功能的全面概述.
  • 强调口腔免疫在维持耐受性和启动防御方面的双重作用.
  • 在口腔免疫学中探索治疗点和新技术.

主要方法:

  • 对口腔免疫学现有文献的综述.
  • 讨论面发育和骨重塑中的免疫机制.
  • 突出了单细胞RNA测序 (scRNA-seq),空间转录组学,元基因组学和多基因组学整合方面的进展.

主要成果:

  • 口腔免疫失调症可以导致局部炎症状况和全身免疫障碍.
  • 免疫机制对于面发育和骨再生至关重要.
  • 新技术使得口腔免疫相互作用的高分辨率表征成为可能.

结论:

  • 口腔免疫对于将局部粘膜防御与全身免疫反应联系起来至关重要.
  • 了解口腔免疫机制对于疾病发病和向干预至关重要.
  • 免疫检查点抑制剂和微生物组导向疗法等治疗策略显示出恢复免疫平衡的希望.