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Updated: Jan 11, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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针对VISTA的向破坏可以增强抗瘤免疫疗法

Li Chen1, Xia Bu2, Yishuang Sun3

  • 1Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Cell research
|November 12, 2025
PubMed
概括

研究人员发现了一种针对癌症免疫治疗的V-域Ig抑制T细胞激活 (VISTA) 的新方法. 抑制USP2降低VISTA,促进T细胞反应,并改善抗PD-1治疗的生存率.

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