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在野生和受养的尾 (Macaca arctoides) 中对肠道微生物组进行比较的元编码分析

Nur Azimah Osman^1,2, Abd Rahman Mohd-Ridwan³, Millawati Gani^1,4

¹Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.

Journal of medical primatology

|November 12, 2025

概括

这项研究揭示了马来西亚野生和养殖的尾 (Macaca arctoides) 的肠道微生物群. 他们的肠道细菌和环境之间没有发现显著差异.

科学领域:

微生物学微生物学
灵长类生态学灵长类生态学
基因组学就是基因组学.

背景情况:

胃肠道是细菌的息地,可能受到息地的影响.
野生和被捕的马来西亚长尾 (Macaca arctoides) 的肠道微生物组仍然没有特征.
了解灵长类肠道微生物群对于生态和健康研究至关重要.

研究的目的:

描述马来西亚半岛野生和受囚禁的M. arctoides肠道微生物组合.
研究肠道微生物群落与宿主外部环境之间的关系.
为了建立未来研究尾肠道健康和潜在的动物传染病原体的基准.

主要方法:

来自野生和被捕的M. arctoides的便样本使用便metabarcoding方法进行分析.
使用MiSeq平台进行了16S rRNA基因测序,共进行了300次对结读.
生物信息学分析确定了细菌类,序列,家族,属和物种.

主要成果:

确定了多样化的肠道微生物组,包括18个类,38个序列,46个家族,76个属和131个物种.
最丰富的细菌家族是Firmicutes,Spirochaetes和Proteobacteria. 这些细菌家族最为丰富.
野生和被捕或它们的息地之间没有观察到肠道微生物组合的实质性差异.

结论:

这项研究提供了马来西亚半岛野生的肠道微生物组的第一个全面的记录.
肠道微生物组合的M. arctoides似乎适应环境变化.
需要进一步的研究来评估与尾肠道微生物群相关的潜在动物感染风险.

关键词:

这是Cercopithecidae的第一个.临灭绝的灵长类动物.我们的肠道微生物组.高通量测序的测序方法马可克 (Macaque) 是一个巨.

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