儿童喘非药物干预的有效性:系统性审查和网络元分析
Jia Zhang1, Zhen Ye2, Fangyang Guo1
1Integrated Chinese and Western Medicine Institute for Children Health & Drug Innovation, Jiangxi University of Chinese Medicine, Discipline of Chinese and Western Integrative Medicine, Nanchang, 330004, Jiangxi, China.
BMC pediatrics
|November 13, 2025
概括
非药物干预显著改善了儿童喘症状. 运动训练增强了肺功能 (FEV1,FVC,PEF),而心理干预和按摩疗法为喘管理提供了额外的好处.
科学领域:
- 儿科肺病学 儿科肺病学
- 综合医学是一个整体的医学.
- 呼吸系统健康 呼吸系统健康
背景情况:
- 儿童喘是一种常见的慢性呼吸道疾病.
- 药物治疗,如吸入性皮质类固醇是标准的.
- 非药物干预措施在改善喘结果方面表现有前途.
研究的目的:
- 系统评估儿童喘各种非药物干预措施的疗效.
- 进行网络元分析 (NMA),比较各种互补疗法.
- 确定儿童喘管理的最佳辅助治疗方法.
主要方法:
- 搜索了七个数据库,查找截至2025年4月的随机对照试验 (RCT).
- 使用Cochrane偏差风险工具评估偏差风险.
- 使用R和Stata软件进行了网络元分析.
主要成果:
- 包括3164名参与者的41项研究.
- 干预措施包括运动,呼吸技巧,炼,心理支持和按摩.
- 所有非药物干预都改善了喘症状;运动训练显著改善了FEV1,PEF和PAQLQ.
结论:
- 五种非药物干预措施有效地缓解了儿童喘症状.
- 心理干预优化了FEV1,而运动训练改善了FVC.
- 按摩疗法对PEF,PAQLQ得分和FeNO水平产生了更好的影响.
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