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食物,地中海饮食和多病症风险:来自大型基于人口的队列研究的结果
Huifeng Zhang1,2, Xing Wang1, Peiwen Shi1
1Department of Health Management, Tangdu Hospital, Fourth Military Medical University, No. 569, Xinsi Road, Baqiao District, Xi'an, 710038, Shaanxi Province, China.
坚持地中海饮食可能会降低多病风险,而高肉类消费,特别是加工肉类,会增加多病风险. 这些饮食因素为慢性疾病提供了潜在的预防策略.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 多发病症是一个重大的全球健康挑战.
- 关于可改变的饮食因素影响多发病风险的证据有限.
研究的目的:
- 调查饮食模式,特别是遵守修改的地中海饮食和肉类消费,与发展多病症的风险之间的关联.
- 通过年龄和身体质量指数 (BMI) 探索潜在的效果修改.
主要方法:
- 一项对35372名年龄在35-69岁之间的英国女性队列的纵向研究.
- 用217项食物频率调查问卷评估的饮食摄入量.
- 通过使用ICD代码的查尔森并发症指数 (CCI) 定义的多发症.
- 考克斯比例危险模型用于估计关联,根据年龄和BMI进行子组分析.
主要成果:
- 较高的地中海饮食坚持与降低多病性风险有关 (HR 0.86对于高度坚持).
- 增加加工肉 (HR 1.60),红肉 (HR 1.19) 和全肉 (HR 1.12) 的摄入量与更高的多种疾病风险有关.
- 关联通常在各个子组中进行,尽管地中海饮食的影响在60岁以上的女性中减弱.
结论:
- 坚持地中海饮食显示出对多病症的保护作用.
- 肉类的高消费,特别是加工肉类,与多种疾病的风险增加有关.
- 饮食修改是预防多病症的有希望的目标,需要在不同人群中进行进一步的研究.
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