预测腹腔透析患者的肉症:基于多模式超声波的物流回归分析和诺莫格拉姆模型
Shengqiao Wang1, Xiuyun Lu1, Juan Chen1
1Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai JiaoTong University, School of Medicine, 1665th Kongjiang Road, Shanghai 200092, China.
Diagnostics (Basel, Switzerland)
|November 13, 2025
概括
这项研究开发了一种多式超声波模型,用于预测腹腔透析患者的肉症. 该模型有效地识别了高风险的个体,使得早期干预能够获得更好的结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 诊断成像 诊断成像 诊断成像
背景情况:
- 皮症是经过腹膜透析 (PD) 的患者常见的并发症.
- 早期检测sarcopenia对于管理PD患者和改善他们的生活质量至关重要.
- 当前的诊断方法可能在可访问性和侵入性方面存在局限性.
研究的目的:
- 评估基于多式超声波的逻辑回归和名谱模型的诊断价值,用于预测PD患者的肉症.
- 在这个人群中开发和验证一种非侵入性预测工具来预测sarcopenia.
主要方法:
- 178名PD患者被招募并根据2019年亚洲肉症工作组 (AWGS) 标准分为肉症和非肉症组.
- 测量了多模式超声波参数 (肌肉厚度,角,带长度,衰减系数,回声强度) 的胃半径中间头部.
- 构建了二进制后勤回归和名图模型,并使用接收器操作特征 (ROC) 曲线评估了它们的准确性.
主要成果:
- 与非萨科佩尼亚患者相比,患有萨科佩尼亚的患者的肌肉厚度,皮纳角和带长度显著降低,衰减系数和回声强度更高 (p < 0.05).
- 一个多式超声波后勤回归模型实现了0.785的F1得分和0.902.90的ROC曲线下的面积 (ROC-AUC).
- 与通过生物电阻分析 (BIA) 测量的尾骨肌指数 (ASMI) 相比,名图没有显示任何统计差异.
结论:
- 开发的多式超声波预测模型有效地识别了患有高风险的肉类的PD患者.
- 这种非侵入性工具可以帮助临床医生进行早期检测和干预,从而有可能改善临床结果.
- 基于超声波的评估为PD患者的查提供了一个有希望的替代方案.
相关概念视频
Peritoneal Dialysis III: Nursing Management
630
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
630
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
178
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
178


