脑输液光学在诊断工具箱中用于确认脑死亡:实用方面和检查协议
Albrecht Günther1, Anne Gunkel1, Christian Geis1
1Department of Neurology, Jena University Hospital, 07747 Jena, Germany.
Diagnostics (Basel, Switzerland)
|November 13, 2025
概括
脑 perfusion 扫描 (BPS) 可靠地通过检测循环停止来确认脑死亡 (BD). 这种安全可行的测试提供了明确的结果,即使在复杂的病例中,临床状态或设备支持是不确定的.
科学领域:
- 神经学 神经学
- 核医学是一种核医学.
- 关键护理医学 关键护理医学
背景情况:
- 临床检查是确定脑死亡 (BD) 的标准.
- 确认性测试通常是必要的,特别是在不确定的发现或药物相互作用的情况下.
- 脑输液光学 (BPS) 是一种公认的评估大脑循环停止的方法.
研究的目的:
- 评估BPS在诊断BD中的可行性,安全性和技术稳定性.
- 评估BPS在不同患者群体中的疗效,包括那些临床状况或机械支持不确定的患者.
主要方法:
- 由神经密集型专家进行的标准化临床BD评估.
- 使用99m的Tc-hexamethylpropyleneamine oxime (HMPAO) 的辅助BPS.
- 预期记录成像,确认性测试结果和临床参数.
主要成果:
- 在30名患者中进行了BPS,在所有患者中证明了脑 perfusion 的停止.
- 测试甚至在患有去压缩切除术 (DC),静脉动脉外体膜氧化 (vaECMO) 或左心室辅助装置 (LVAD) 的患者中也取得了成功.
- 没有发生任何技术故障,结果是明确的,特别是在复杂的情况下.
结论:
- BPS是一种可行的,安全的,技术上可靠的BD诊断确认测试.
- BPS提供了明确的结果,特别是在新生儿,儿童,DC后患者和机械循环支持患者中.
- 该技术适用于用LVAD和vaECMO支持的患者,增强诊断能力.
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