在FIT阳性患者中,常规胃镜的诊断收益有限
Majd Khader1,2, Fadi Abu Baker3,4, Jorge-Shmuel Delgado1,2
1Gastroenterology Institute, Assuta Medical Center, Beer-Sheva 8489507, Israel.
Diagnostics (Basel, Switzerland)
|November 13, 2025
概括
在便免疫化学测试阳性患者的常规胃镜检查具有有限的价值. 临床意义上的上部胃肠病变很少见,即使结肠镜检查结果正常.
科学领域:
- 胃肠病学 胃肠病学
- 诊断内镜检查 诊断内镜检查
- 公共卫生查 公共卫生查
背景情况:
- 便免疫化学测试 (FIT) 是对结直肠癌的查工具.
- 在正常结肠镜检查的FIT阳性患者中,常规胃镜检查的作用尚不清楚.
- 在FIT阳性个体中调查上部肠道病变对于优化诊断途径至关重要.
研究的目的:
- 通过胃镜检查在FIT阳性患者中发现的上部胃肠道 (GI) 病变的患病率和临床意义.
- 为了比较肠镜检查结果正常与异常结肠镜检查结果的患者之间的胃镜检查结果.
- 在这个人群中评估常规胃镜的诊断产量.
主要方法:
- 从2016年到2022年,对38392名FIT阳性成年人 (≥18岁) 的回顾性分析.
- 包括1560名接受双向内镜 (结肠镜和胃镜) 的患者.
- 根据结肠镜检查结果分析和比较胃镜检查结果 (胃炎,腹腔,食道炎,十二指肠炎,,恶性瘤).
主要成果:
- 在1560名患者中,632名 (40.5%) 的结肠镜检查正常,928名 (59.5%) 的结肠镜检查异常.
- 胃炎是常见的 (55.5%对比48.7%),缺口 (15%对比14.9%),食道炎 (9.0%对比10.3%),以及十二指肠炎 (6.6%对比7.3%).
- 临床上显著的病变,如胃 (0.95-1.29%) 和上部胃肠道恶性瘤在两组中都是罕见的.
结论:
- 在FIT阳性患者的常规胃镜检查具有有限的诊断价值.
- 在FIT阳性个体中,临床意义上的上部肠道病变并不常见,无论结肠镜检查结果如何.
- 目前的指导方针可能需要重新评估在这个患者队列中常规胃镜检查.
关键词:
这就是FITIT.异常结肠镜检查异常结肠镜检查腺瘤检测率 (ADR) 是指结肠直肠癌是什么意思胃镜检查 (gastroscopy) 是一个可以检查胃的方法.通常的结肠镜检查是正常的.聚合物检测率 (PDR) 是指聚合物的检测率.更多相关视频
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