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Updated: Jan 11, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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在PRDM16和SREBP路径之间的功能相互作用控制脂质代谢

Hafiz Majid Mahmood1, Maria Teresa Bengoechea-Alonso1, Dana E Al-Ansari2

  • 1College of Health and Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.

International journal of molecular sciences
|November 13, 2025
PubMed
概括

含有16 (PRDM16) 的PRDI-BF1和RIZ同质域抑制了固醇调节元素结合蛋白1和2 (SREBP1/2) 相关的脂质代谢. PRDM16的不活化增强了SREBP1/2的活性,增加了脂质合成和脂肪生成,影响了代谢疾病.

关键词:
这是BATBATBAT.在PRDM16中,我们可以看到:对于SREBP来说,这是一个很好的选择.这是什么?是什么?是什么?脂质生成 (adipogenesis) 是一种胆固醇 胆固醇 胆固醇 是一种糖尿病 糖尿病患者 糖尿病患者胰岛素的信号传递方式脂质新陈代谢 脂质新陈代谢

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