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Updated: Jan 11, 2026

Generation of Murine Monoclonal Antibodies by Hybridoma Technology
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Generation of Murine Monoclonal Antibodies by Hybridoma Technology

Published on: January 2, 2017

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为单克隆抗体发现和开发的技术.

Kyung Ho Han1, Yi-Chuan Li2,3, Rabia Parveen4

  • 1Department of Biological Sciences and Biotechnology, Hannam University, Daejeon 34054, Republic of Korea.

International journal of molecular sciences
|November 13, 2025
PubMed
概括

单克隆抗体的发现使用各种方法,如混合体技术和菌体显示. 人工智能和抗体库的创新加速了针对各种疾病的向生物治疗药物的开发.

关键词:
抗体是一种抗体.抗体工程是针对抗体的工程.这就是de novo合成.在这种情况下,hybridoma就是hybridoma.菌体显示器可以显示菌体.

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相关概念视频

Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
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