相关实验视频

Updated: Jan 11, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy

Published on: October 20, 2011

口腔中的微生物凝聚:分子相互作用和当前见解

Yuichi Oogai¹, Yumika Tanaka^1,2, Masanobu Nakata¹

¹Department of Oral Microbiology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan.

International journal of molecular sciences

|November 13, 2025

概括

牙周炎是由有害细菌驱动的,与严重的全身疾病有关. 牙斑中的细菌凝聚是疾病发展和传播的关键.

科学领域:

口腔微生物学口腔微生物学
牙周病研究牙周病研究
微生物的病原发生.

背景情况:

牙周炎是一种慢性炎症状况,由异生性口腔细菌引起.
牙周病原体与糖尿病,心血管疾病,癌症和不良妊娠结果等全身性疾病有关.
主要的病原体包括*Porphyromonas gingivalis*,*Prevotella intermedia*,*Treponema denticola*,*Tannerella forsythia*,*Aggregatibacter actinomycetemcomitans*和*Fusobacterium nucleatum*.这些病原体都被认为是人类体内的疾病.

研究的目的:

审查当前有关细菌相互作用的知识,特别是主要牙周病原体之间的凝聚.
讨论凝聚在牙周炎发病的作用.
探索协集对与牙周炎相关的全身性疾病的影响.

主要方法:

关于牙周病原体及其相互作用的研究文献综述.
专注于凝聚机制及其对生物膜形成的影响.
分析物种间细菌相互作用在疾病进展中的作用.

主要成果:

跨物种的聚合对于牙斑的成熟和病原性微生物群落的建立至关重要.
凝聚会影响细菌的空间组织,生存和生物膜内的毒性因子表达.
了解这些相互作用对于理解牙周炎及其全身表现至关重要.

结论:

牙周病原体之间的细菌凝聚是牙周炎发展的重要因素.
这些相互作用有助于牙周炎和相关系统性疾病的发病.
对凝聚机制的进一步研究可以为牙周炎和相关疾病的治疗策略提供信息.

关键词:

这种细菌名为Fusobacterium nucleatum.联合聚合联合聚合联合聚合牙周病原体是牙周病原体.红色复合体红色复合体

更多相关视频

Use of a High-throughput In Vitro Microfluidic System to Develop Oral Multi-species Biofilms

Use of a High-throughput In Vitro Microfluidic System to Develop Oral Multi-species Biofilms

Published on: December 1, 2014

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface

Published on: July 4, 2018

相关概念视频

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...

Coagulation

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...

Gene Regulation in Microbial Communities: Quorum Sensing

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...