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Updated: Jun 16, 2026

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识别与microRNA相关的向基因,用于发展视觉器官

Sehee Lee1, Sungjin Park2,3, Euyhyun Park1

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, Korea University Anam Hospital, 73 Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.

International journal of molecular sciences
|November 13, 2025
PubMed
概括

新生小鼠内耳器官中的细胞外囊 (EV) 含有调节发育的微RNA (miRNA). 这些EV miRNA在分化过程中被下调,为听力恢复疗法提供了潜力.

关键词:
发展发展发展发展发展.不同化的差异化差异化.细胞外囊泡中的细胞外囊泡.内耳的有机体内耳这就是miRNAs.复兴再生是一种再生方式.

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MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...