来自Flavobacterium psychrophilum的Fp2Cas9,一种冷适应的II-C型CRISPR核酶的功能性表征

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Ran Zhao1, Jianqiang Zhu1, Jing Wang1

  • 1Key Laboratory of Aquatic Animal Diseases and Immune Technology of Heilongjiang Province, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China.

International journal of molecular sciences
|November 13, 2025
PubMed
概括

研究人员发现了Fp2Cas9,这是一种来自*Flavobacterium psychrophilum*的冷活性Cas9酶. 这种酶在低温下有效编辑基因组,扩大了在寒冷环境中的CRISPR应用.

关键词:
这种细菌名为Flavobacterium psychrophilum.在Fp2Cas9PAM的特异性是PAM的特异性.适应寒冷的Cas9斑马鱼的基因组编辑

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