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Updated: Jan 11, 2026

Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups
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Hydrolysis of a Ni-Schiff-Base Complex Using Conditions Suitable for Retention of Acid-labile Protecting Groups

Published on: April 6, 2017

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合成,物理化学表征和三种新型阿米诺酸衍生的 Schiff 基体的生物杀伤性评估,其中包括具有分子内结合的基体

Alexander Carreño1,2, Vania Artigas2, Belén Gómez-Arteaga2

  • 1Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 275, Santiago 8370146, Chile.

International journal of molecular sciences
|November 13, 2025
PubMed
概括

希夫基的化增强了它们的抗微生物特性,有的化合物显示出对格拉姆阳性细菌的选择性强度和降低了毒性. 这项研究确定了开发新抗菌剂的有希望的支架.

关键词:
在LHS中,LHS是LHS.欧洲议会的欧洲议会议员船舶基地是船舶的基地.在X射线晶体学.氨基enzoic 酸 的使用.生物制药活动生物制药活动循环电压测量是指循环电压测量.整个细胞的活力.分子内部的结.

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Basicity of Heterocyclic Aromatic Amines

Heterocyclic amines, where the N atom is a part of an alicyclic system, are similar in basicity to alkylamines. Interestingly, the heterocyclic amine having a nitrogen atom as part of an aromatic ring has much less basicity than its corresponding alicyclic counterpart. For this reason, as presented in Figure 1, piperidine (pKb = 2.8) is significantly more basic than pyridine (pKb = 8.8).
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To measure the basicity of amines, two conventions are generally used. The first defines Kb as the basicity constant for the deprotonation reaction of water by the amine, as presented in Figure 1. Conventionally, lower Kb indicates higher...
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Aminolysis is a nucleophilic acyl substitution reaction, where ammonia or amines act as nucleophiles to give the substitution product. Acid halides react with ammonia, primary amines, and secondary amines to yield primary, secondary, and tertiary amides, respectively.
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