怀孕期间心血管风险:临床影响和长期后果的范围审查
Maria Morales-Suarez-Varela1,2, Francisco Guillen-Grima2,3,4,5
1Research Group in Social and Nutritional Epidemiology, Pharmacoepidemiology and Public Health, Department of Preventive Medicine and Public Health, Food Sciences, Toxicology and Forensic Medicine, Faculty of Pharmacy and Food Sciences, Universitat de València, 46100 Burjassot, Spain.
怀孕可以揭示隐藏的心血管风险,增加未来心脏病的可能性. 怀孕期间早期识别和管理对于母亲和婴儿健康至关重要.
科学领域:
- 心血管健康 心血管健康
- 生殖医学 生殖医学
- 公共卫生 公共卫生
背景情况:
- 怀孕涉及显著的生理变化,可以揭露或触发潜在的心血管风险因素.
- 妊娠并发症,如子宫前和妊娠糖尿病,与长期心血管疾病 (CVD) 风险有关.
- 在怀孕期间评估心血管风险 (CVR) 对于及时干预和改善母亲/胎儿结果至关重要.
研究的目的:
- 检查怀孕期间的心血管风险及其长期后果.
- 提供关于心血管变化和怀孕的综合性视角.
- 确定怀孕期间CVR的病因,诊断和治疗方面.
主要方法:
- 根据PRISMA-ScR指南进行了范围审查.
- 在PubMed,Embase和Scopus (2019-2024) 中进行了文献搜索.
- 在205个最初识别的文章中,有20个符合分析的纳入标准.
主要成果:
- 怀孕就像一个"心血管应力测试",揭示了潜在的CVR.
- 产科并发症与未来心血管疾病风险的增加有关.
- 遗传因素和生物标志物对CVR评估有希望;个性化管理策略是有效的.
结论:
- 怀孕为早期CVR识别和管理提供了一个关键的窗口.
- 产科并发症显著增加了未来心血管疾病的可能性.
- 怀孕期间的干预对于改善母亲/新生儿的结果和减少长期心血管疾病的发生至关重要.
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