时间型,夜班工作和医疗保健专业人员的白天唾液皮质醇节律
Katalin Fusz1, András Deák2, Péter Závodi1,3
1Institute of Physiology, Medical School, University of Pécs, 7624 Pécs, Hungary.
Journal of clinical medicine
|November 13, 2025
概括
医疗保健工作者的晚间时间型与睡眠质量差以及压力激素调节的改变有关. 了解时间型可以改善轮班工作安排和更好的职业健康干预措施.
科学领域:
- 职业健康 职业健康 职业健康
- 时间生物学 时间生物学
- 内分泌学 在内分泌学.
背景情况:
- 时型影响轮班工作耐受性,但其与医疗保健工作者压力和睡眠的联系尚未得到充分研究.
- 轮班工作在护士和医生中很普遍,影响他们的健康和福祉.
- 了解时间型的相关性对于优化医疗保健劳动力管理至关重要.
研究的目的:
- 调查轮班医疗保健专业人员的时间型,感知压力,睡眠质量和健康行为之间的关联.
- 描述白天唾液皮质醇模式与日夜班的时间型相关的特征.
- 在这个人群中确定失眠的危险因素.
主要方法:
- 对451名轮班护士和医生的横截面研究.
- 经过验证的问卷评估了感知到的压力 (PSS),失眠 (AIS),人体症状 (PHQ-15) 和时间型 (rMEQ).
- 一项试点副研究测量了40名护士的唾液皮质醇在白天和夜间班次.
主要成果:
- 晚间时间型与更高的失眠率 (70%) 和更差的睡眠质量 (AIS分数) 相关.
- 晚间类型的皮质醇唤醒反应减弱,白天班次的白天皮质醇倾斜率更平坦.
- 增加的年龄,身体负担和感知到的压力预测了失眠;清晨是保护性的.
结论:
- 医疗保健专业人员的晚间时间型与下丘脑-垂体-上腺轴活动失调和睡眠障碍相关.
- 基于时刻型的日程安排和针对昼夜失调的干预措施可能会改善职业健康结果.
- 这些发现强调了在轮班工作环境中考虑个体时代生物学的重要性.
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