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相关概念视频

Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Pulmonary Embolism I: Introduction01:29

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
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Pleural Effusion II: Symptoms and Management01:28

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
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恶性疾病相关的肺栓塞:死亡率,复发和出血风险

Daniela Maria Nemțuț1, Florica Voiță-Mekeres1,2, Ruxandra Ulmeanu1

  • 1Doctoral School of Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.

Journal of clinical medicine
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PubMed
概括

肺栓塞 (PE) 的癌症患者面临更高的晚期死亡率,受年龄和癌症状况的影响,而不是早期的结果. NT-proBNP可能有助于PE患者的风险分层.

关键词:
NT-proBNP 的国家统计.与癌症相关的血栓形成.直接的口服抗凝剂 直接的口服抗凝剂肺栓塞 肺栓塞是一种肺栓塞.

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科学领域:

  • 心脏病学 心脏病学
  • 在瘤学瘤学.
  • 肺部病理学 肺部病理学

背景情况:

  • 肺栓塞 (PE) 是一个重要的死亡原因,结果受到患者因素和治疗的影响.
  • 直接口服抗凝剂 (DOAC) 越来越多地使用,但PE癌症患者的真实数据有限.
  • 将患有PE的癌症和非癌症患者进行比较对于理解不同结果至关重要.

研究的目的:

  • 为了比较人口统计学,临床特征,治疗策略和急性PE瘤患者与非癌症患者的结局.
  • 确定影响PE患者癌症和无癌症早期和晚期死亡的因素.
  • 评估NT-proBNP作为PE风险分层的生物标志物的作用.

主要方法:

  • 2019年1月至2021年12月,对226名急性PE成人患者 (106名癌症患者,120名非癌症患者) 的多中心回顾性队列研究.
  • 收集的数据包括人口统计,并发症,实验室生物标志物 (NT-proBNP,D-二次体),抗凝策略 (VKA,DOAC) 和结果.
  • 主要结局是≤30天和31-365天的所有原因死亡率;次要结局包括PE复发和出血事件.

主要成果:

  • 癌症患者年龄较大,NT-proBNP水平较高,而非癌症患者的D-二次体水平较高.
  • 与非癌症患者 (65.0%) 相比,癌症患者 (40.6%) 使用DOAC的频率较低.
  • 早期死亡率相似,但晚期死亡率在癌症患者中明显高 (38.7%对3.3%). 多变量分析将癌症状况和年龄与较高的晚期死亡率联系起来.

结论:

  • 及时的抗凝剂与PE患者的早期死亡率降低有关.
  • 癌症和非癌症PE患者之间的晚期死亡率差异受到年龄和癌症状况的显著影响.
  • NT-proBNP可能是PE风险分层的一个有价值的生物标志物,需要在前性研究中进一步调查.