蝙蝠物种的细菌组成:从人类健康的角度看
Julio David Soto-López1, Pedro Fernández-Soto1,2, Antonio Muro1
1Infectious and Tropical Diseases Research Group (e-INTRO), Biomedical Research Institute of Salamanca, Research Centre for Tropical Diseases (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, 37008 Salamanca, Spain.
Animals : an open access journal from MDPI
|November 13, 2025
概括
蝙蝠含有许多与人类健康相关的细菌病原体. 对最近的研究进行的一项审查显示,与蝙蝠相关的细菌多样化,包括重要的人类病原体,强调需要综合监测.
科学领域:
- 微生物学 微生物学
- 动物传播疾病 动物传播疾病
- 环境健康 环境健康
背景情况:
- 蝙蝠是众所周知的各种细菌病原体的储存库,对公共卫生有影响.
- 最近的动物传染病爆发增加了对蝙蝠微生物组和微生物多样性评估的高通量测序的关注.
研究的目的:
- 审查过去五年关于与蝙蝠相关的细菌物种的文献.
- 评估这些细菌的潜在临床相关性,并确定研究趋势.
主要方法:
- 在过去五年内发表的47项同行评审研究中进行了自动搜索和手动过.
- 专注于关于细菌物种,样本类型 (瓜诺,皮肤) 和测序方法的数据提取.
主要成果:
- 鉴定了与蝙蝠相关的4700种细菌,包括已知的有气溶传播或机会性感染潜力的人类病原体.
- 注意到对瓜诺样本的研究占主导地位,对皮肤微生物群的兴趣日益增加,特别是关于白鼻综合征.
- 中国和美国领先出版物,用片测序作为主要的元基因组学方法.
结论:
- 蝙蝠相关细菌包括许多临床关注的物种,其中一些为抗菌药物开发优先考虑.
- 由于相关疾病的临床严重程度,将蝙蝠纳入流行病监测至关重要.
- 缺乏标准化的报告实践,阻碍了对蝙蝠微生物群数据的强有力的生态和流行病学分析.
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