三糖醇结晶性和乳液体酸稳定性的影响在体外消化中长链欧米茄-3脂肪酸丰富纳米乳液的脂解和生物可访问性
Jessica D Ulbikas1, Saeed Mirzaee Ghazani2, Alejandro G Marangoni2
1Department of Human Health Sciences, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada.
Foods (Basel, Switzerland)
|November 13, 2025
概括
乳液稳定性和脂肪晶体结构影响消化和多可萨赫萨酸 (DHA) 吸收. 酸稳定的乳液和较少的晶体脂肪在体外消化过程中提高了DHA的生物可访问性.
科学领域:
- 食品科学 食品科学 食品科学
- 合体和表面科学科学
- 营养科学 营养科学
背景情况:
- 乳液稳定性对于营养物质的输送和消化至关重要.
- 三糖醇 (TAG) 的结晶性和体酸的稳定性会在消化过程中影响乳液的命运.
- 多可萨赫萨酸 (DHA) 的生物可访问性受乳液微观结构和消化条件的影响.
研究的目的:
- 为了研究TAG结晶性和体酸稳定性对乳液微结构,脂解和DHA在体外消化过程中的生物可访问性的影响.
- 确定乳化剂类型和冷却速度如何影响乳液特性和消化结果.
- 为了确定乳液特性和DHA吸收之间的关系.
主要方法:
- 制造具有不同TAG组成的油在水纳米乳液 (棕油脂或油脂) 和乳化剂 (酸稳定的Tween 80或酸不稳定的大豆莱素).
- 控制冷却以诱导不同的TAG物理状态 (结晶性).
- 评估颗粒大小,泽塔潜力和乳液微观结构.
- 在体外消化使用INFOGEST静态模型来测量脂解和DHA生物可访问性.
主要成果:
- 酸不稳定的乳液 (大豆莱西丁) 显示胃相聚合,导致脂解缓慢.
- 棕胆固醇乳液由于TAG结晶性而表现出较低的脂解.
- 实现了高的DHA生物可访问性,特别是与酸稳定的乳液 (Tween 80).
结论:
- 乳液体酸的稳定性显著影响胃微观结构和消化.
- TAG的物理状态 (结晶性) 影响脂解速率.
- 优化乳液稳定性和TAG结构可以提高DHA的生物可访问性,这对于营养应用至关重要.
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