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炎症性肠病的管理与癌症史的炎症性肠病的管理
Vito Annese1,2, Marzio Parisi3, Sofia Cinque1,4
1Unit of Gastroenterology, IRCCS San Donato Policlinic, San Donato Milanese, 20097 Milan, Italy.
管理患有癌症的炎症性肠病 (IBD) 患者需要仔细考虑癌症风险和治疗剂. 本综述审查了当前的指导方针和现实数据,以获得最佳的患者护理.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 临床医学 临床医学
背景情况:
- 炎症性肠病 (IBD) 患者由于慢性炎症,遗传和衰老而存在复杂的癌症风险.
- 在IBD管理中使用的治疗剂也可能影响癌症的发展或复发.
- 临床实践缺乏强有力的指导方针来管理有癌症史的IBD患者.
研究的目的:
- 审查当前的指导方针和现实世界的证据,以管理IBD患者的癌症.
- 分析IBD,其治疗方法和癌症风险之间的相互作用.
- 为此患者群体的查,预防,监测和治疗适应提供见解.
主要方法:
- 对现有的共识指南进行系统审查.
- 从最近的患者队列中分析现实世界的数据.
- 关于IBD患者癌症风险因素和治疗影响的文献综合.
主要成果:
- 关于癌症IBD患者最佳管理策略的数据有限.
- 在IBD中癌症风险是多因素的,包括疾病活动和治疗干预措施.
- 现实世界的数据提供了管理方法的新兴证据.
结论:
- 了解IBD癌症风险对于临床管理至关重要.
- 评估IBD治疗对癌症的影响至关重要.
- 对于有癌症病史的IBD患者来说,需要制定量身定制的查,监测和治疗策略.
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