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解决透析患者营养不良问题的营养策略:系统性审查
Paula Arroyo-Serrano1, Rosario Alonso-Dominguez1,2, Sebastián Mas-Fontao3,4,5
1Department of Nursing and Physiotherapy, University of Salamanca, 37008 Salamanca, Spain.
Nutrients
|November 13, 2025
概括
营养干预措施有效地打击透析患者的蛋白质能量浪费 (PEW). 诸如口服补充剂和腹腔内透析辅助营养等策略可以改善营养状况,肌肉质量和生活质量,降低发病和死亡风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 公共卫生 公共卫生
背景情况:
- 蛋白质能量浪费 (PEW) 是慢性病 (CKD) 患者接受透析的普遍并发症.
- 在这个患者群体中,PEW显著增加了发病率,死亡率,并降低了生活质量.
- 有效的营养管理对于改善透析患者的治疗结果至关重要.
研究的目的:
- 系统地审查各种营养策略在改善透析患者营养状况方面的有效性.
- 评估干预措施,如口服营养补充剂和腹腔内透析亲肠营养.
- 确定最佳的营养方法,以预防和治疗CKD患者的PEW在透析.
主要方法:
- 根据PRISMA声明进行了系统审查.
- 在PubMed,BVS和Scopus数据库中进行了搜索.
- 包括随机或受控的临床试验,涉及成人血液透析 (HD) 或腹腔透析 (PD) 患者.
主要成果:
- 营养干预表明生物化学标志物如血清白蛋白的持续改善.
- 在肌肉质量,炎症标志物和感知到的生活质量方面观察到积极的影响.
- 内透析补充剂和多学科护理对中度至重度营养不良的患者尤其有益.
结论:
- 营养不良是透析患者中常见且具有临床意义的问题.
- 营养策略,包括口服补充剂,内透析亲肠营养 (IDPN) 和个性化咨询,在管理PEW方面是有效的.
- 早期,量身定制,基于证据和多学科的营养干预措施可以显著改善透析患者的临床预后和生活质量.
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