Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Improving Translational Accuracy02:07

Improving Translational Accuracy

14.0K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
14.0K
Improving Translational Accuracy02:07

Improving Translational Accuracy

3.5K
3.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Comparative analysis of hyaluronic acid fillers: Juvéderm Volux versus MaiLi Extreme in microstructural, rheological and mechanical properties.

JPRAS open·2026
Same author

Prognostic value and potential upstream regulator of Schwann cells in esophageal squamous cell carcinoma.

Translational cancer research·2026
Same author

A Hand-Held Digital Printer for On-Site Fabrication of Micro/Nano Composite Dressings.

ACS applied materials & interfaces·2026
Same author

Nrf2/HO-1 Dysregulation is Involved in the Microplastic-Induced Gut-Liver Axis Damage Mechanism and the Protective Effect of Astaxanthin.

Journal of agricultural and food chemistry·2026
Same author

Thoracoscopic resection of the second rib via a periareolar approach: a case report.

Journal of cardiothoracic surgery·2026
Same author

Probiotic characterization of Ligilactobacillus murinus ZQL11 isolated from healthy dog feces.

Veterinary research communications·2026
Same journal

AI foundation models in plant biology.

The New phytologist·2026
Same journal

BpMYB73 regulates long noncoding RNA BplncW20 to improve drought tolerance by mediating ROS scavenging in Betula platyphylla.

The New phytologist·2026
Same journal

Soil fertility controls on tropical forest productivity and mortality: synthesis and roadmap.

The New phytologist·2026
Same journal

Global patterns of C<sub>3</sub>/C<sub>4</sub> grass biomass allocation: how aridity mediates nitrogen-induced divergent strategies.

The New phytologist·2026
Same journal

Root hair plasticity in cereals under abiotic stress.

The New phytologist·2026
Same journal

Hijacked hydraulics: Verticillium dahliae-induced xylem dysfunction in pepper stems revealed by integrated hydraulic, imaging, and molecular analyses.

The New phytologist·2026
查看所有相关文章

相关实验视频

Updated: Jan 11, 2026

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
08:04

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons

Published on: June 6, 2025

1.3K

使用双路径卷积神经网络框架提高基因组选择的准确性:一个类病例研究.

Fuchuan Han1,2, Ming Gao1,2, Yunxiao Zhao1,2

  • 1State Key Laboratory of Tree Genetics and Breeding, Chinese Academy of Forestry, Beijing, 100091, China.

The New phytologist
|November 13, 2025
PubMed
概括
此摘要是机器生成的。

基因组选择加速了森林树木的繁殖. 一个新的深度学习模型,PKDP,通过整合全基因组和GWAS数据,提高了Litsea cubeba中关键类的预测准确性.

关键词:
在Litsea的立方体.在PKDP中,PKDP是PKDP.深度学习是一种深度学习.基因组选择 基因组选择化物是一种化物.

更多相关视频

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images
08:20

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Published on: October 27, 2023

2.4K
Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers
03:37

Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers

Published on: March 1, 2024

1.2K

相关实验视频

Last Updated: Jan 11, 2026

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
08:04

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons

Published on: June 6, 2025

1.3K
Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images
08:20

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Published on: October 27, 2023

2.4K
Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers
03:37

Author Spotlight: Impact of Intergenic Interactions on Disease-Identifying Dark Biomarkers

Published on: March 1, 2024

1.2K

科学领域:

  • 植物遗传学和育种.
  • 基因组学就是基因组学.
  • 代谢学 代谢学 代谢学

背景情况:

  • 基因组选择 (GS) 对于加速森林树木早期繁殖至关重要.
  • 了解类生物合成的遗传基础是改善Litsea cubeba等物种有价值的特征的关键.
  • 传统的育种方法可能很慢,需要先进的基因组工具来进行高效的基因改进.

研究的目的:

  • 为了研究Litsea cubeba中类生物合成的遗传结构.
  • 开发和评估一种基于深度学习的新型基因组选择 (GS) 模型 (PKDP),以提高预测准确度.
  • 为了确定关键的基因和途径,涉及到类合成的分子育种.

主要方法:

  • 从945个Litsea cubeba的生殖质中进行全基因组再测序.
  • 气色谱-质谱法 (GC-MS) 用于在310个样本中量化化物.
  • 全基因组关联研究 (GWAS) 和PKDP深度学习模型的开发,集成GWAS位置和全基因组标记.

主要成果:

  • GWAS确定了125个类生物合成候选基因,包括合成酶 (TPS) 基因群和MVA/MEP通路酶.
  • 与传统的rrBLUP相比,PKDP深度学习模型显示了对关键类 (citral,geranial,neral) 的预测能力提高了2-10%.
  • 影响Litsea cubeba terpenoid合成的关键遗传因素得到了阐明.

结论:

  • 该研究确定了Litsea cubeba terpenoid合成的关键遗传因素,推动了分子机制研究.
  • PKDP模型有效地整合了多个规模的基因组信息,显著提高了GS预测的准确性.
  • 这项研究为Litsea cubeba的遗传改进提供了有效的工具,并提供了创新的策略,用于在森林树木中培育复杂的特征.