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Updated: Jan 11, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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Published on: May 4, 2018

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一种非典型的V形加维辛C细菌素通过域插入准Man-PTS

Aleksandra Tymoszewska1, Kamil Steczkiewicz2, Tamara Aleksandrzak-Piekarczyk2

  • 1Microbiota Lab, Department of Pharmaceutical Microbiology and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), Pawińskiego 5a, 02-106 Warsaw, Poland.

Biophysical journal
|November 13, 2025
PubMed
概括

类似GarC的细菌素使用独特的α螺旋结构来结合曼诺特异性转移酶系统 (Man-PTS) 受体. 这种相互作用形成毛孔,导致细菌细胞死亡,并为抗菌药物设计提供了一条新的途径.

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