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Updated: Jun 22, 2026

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在非结构化N端的酸性补丁调节LSD1活动

Franziska Dukatz1, Hermann Timofeev1, Philipp Schnee1

  • 1Department of Molecular Biochemistry, Institute of Biochemistry, University of Stuttgart, Stuttgart, Germany.

Protein science : a publication of the Protein Society
|November 13, 2025
PubMed
概括

研究人员在氨酸特异性脱甲基酶1 (LSD1) 的N端域中确定了一个关键的酸性区域,揭示了它在调节表观遗传调节和基因表达中的关键作用.

关键词:
在LSD1 (KDM1A) 中.生物分子凝结的生物分子凝结.催化活动的催化活动.在这种情况下,染色染色素染色体子组件 (CSCs) 是一种表观遗传调节 表观遗传调节本质上是无序的区域 (IDR)阶段分离的相位分离.

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