在手动和机动驱动的方法之间的疼痛体验的差异:一个单一中心随机对照试验
Sanjana Sudarshan1, Martyn Sherriff2, Niamh O'Rourke3
1Department of Orthodontics, Royal Surrey County Hospital NHS Foundation Trust, Surrey GU2 7XX, United Kingdom.
European journal of orthodontics
|November 13, 2025
概括
这项研究发现手动和机动驱动的近接间膜缩小 (IER) 技术之间的患者报告的疼痛没有显著差异. 临床医生可以根据效率和偏好选择IER方法,而不是根据疼痛预期.
科学领域:
- 矯正牙科 矯正牙科是一種矯正牙科.
- 牙科研究 牙科研究
- 患者报告的结果
背景情况:
- 靠近间膜缩小术 (IER) 是一种常见的正义牙科手术.
- 现有的IER研究重点是乳液粗性,下风险和牙周健康.
- 患者报告的与不同IER技术相关的疼痛仍未得到充分研究.
研究的目的:
- 为了比较患者在手动与机动驱动的近接间膜缩小 (IER) 过程中报告的疼痛.
- 为了为临床决策提供信息,并加强患者对IER技术的同意.
主要方法:
- 一项前性,随机化,交叉临床试验,涉及34名正牙患者.
- 视觉模拟量表 (VAS) 调查问卷用于测量疼痛.
- 手动和机动驱动IER之间的疼痛分数的比较,使用6周的洗期.
主要成果:
- 在手动 (平均VAS增加18.5毫米) 和电机驱动 (平均VAS增加15.6毫米) IER之间没有观察到统计学上显著的疼痛差异.
- 平均疼痛差异为2.9毫米 (95% CI -1.0至6.8),不具有统计学意义.
- 在VAS评分中,评级者之间和评级者内部的可靠性非常好 (ICC = 1.00).
结论:
- 手动和电机驱动的IER技术导致患者报告的疼痛相似.
- 技术选择应该优先考虑操作员的偏好和效率,而不是疼痛预期.
- 进一步的研究应该调查其他患者报告的结果,如焦虑和治疗持续时间.
相关概念视频
Randomized Experiments
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
Group Design
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between the two are due to...
Controls in Experiments
When conducting an experiment, it is crucial to have control to reduce bias and accurately measure the dependent variables. It also marks the results more reliable. Controls are elements in an experiment that have the same characteristics as the treatment groups but are not affected by the independent variable. By sorting these data into control and experimental conditions, the relationship between the dependent and independent variables can be drawn. A randomized experiment always includes a...
Multiple Comparison Tests
Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Blinding
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.


