在患有 2-4 阶段慢性病的患者中,皮肤透气利切除术后估计的膜过率的变化
Amr H Abou Faddan1, Mohamed Abdelghany1, Adel Kurkar1
1Department of Urology, Faculty of Medicine, Assiut University, Asyut, Egypt.
Urology annals
|November 13, 2025
概括
穿皮瘤切除术 (PCNL) 对于慢性病 (CKD) 患者的大型结石有效. 谨慎的手术技术对于在这些患者中保持功能至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术创新 在外科创新.
背景情况:
- 透皮骨切除术 (PCNL) 是针对大型结石 (≥2厘米) 的标准治疗方法.
- 在慢性病 (CKD) 患者中,PCNL对功能的影响尚未得到充分证实.
- 这项研究侧重于接受PCNL的2至4期CKD患者.
研究的目的:
- 为了前性地评估PCNL后估计的膜过率 (eGFR) 的变化.
- 评估PCNL在CKD患者中的安全性和有效性.
- 为了确定影响PCNL后功能的因素.
主要方法:
- 从2020年12月到2023年12月,对50名患有2-4期CKD的患者进行前性研究.
- 在手术前和手术后3个月使用Cockcroft-Gault公式测量eGFR.
- 还评估了并发症和无结石率 (SFR).
主要成果:
- 80%的患者在PCNL后3个月后表现出改善或稳定的eGFR.
- 在3个月后,无石头率为76%.
- 流血,手术时间,接入次数,石头负担和并发症显著影响了EGFR.
结论:
- PCNL是 2-4 期CKD患者的大型结石的安全有效选择.
- 尽量减少手术时间,出血和入口是预防功能下降的关键.
- 在CKD患者中PCNL结果需要仔细考虑外科因素.
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