肠道微生物群在腹中的作用及其通过针对微生物群的干预措施来缓解腹
Rui Tian1, Chu-Jun Chong1, Ya-Ya Bai1
1Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, and State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and Shaanxi Traditional Chinese Medicine Processing Technology Heritage Base, Shaanxi University of Chinese Medicine, Xi'an, China.
腹与肠道微生物群 (GM) 不平衡有关. 诸如益生菌和便微生物群移植等干预措施可以恢复转基因平衡并缓解腹症状.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 腹是一种常见的胃肠道疾病,与肠道微生物群 (GM) 平衡密切相关.
- 转基因失调影响宿主新陈代谢,免疫功能,肠道屏障和大脑-肠轴,有助于腹的开始和进展.
- 虽然转基因对胃肠道健康和疾病的作用越来越被认可,但确切的机制仍在调查中.
研究的目的:
- 审查与转基因相关的腹发生机制.
- 讨论诸如益生菌,便微生物群移植和菌体治疗等干预措施如何调节转基因来缓解腹.
- 为研究基于转基因的腹机制和临床治疗提供当前参考资料.
主要方法:
- 关于肠道微生物群和腹的基础和临床研究的文献综述.
- 分析转基因失衡导致腹的机制.
- 针对转基因治疗腹治疗的治疗策略的评估.
主要成果:
- 转基因疾病经常伴随患者和动物的腹.
- 与转基因失衡相关的腹包括短链脂肪酸 (SCFA),胆酸 (BA),肠壁功能,免疫反应和脑肠微生物群轴 (BGMA) 的改变.
- 针对转基因的干预措施,包括益生菌,便微生物群移植和菌体治疗,在缓解腹方面表现出有效性.
结论:
- 肠道微生物群在腹的发病过程中起着至关重要的作用.
- 通过各种治疗策略调节肠道微生物群为腹治疗提供了一个有前途的方法.
- 对转基因机制的进一步研究对于推进腹的临床管理至关重要.
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