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两种连续的美国甲状腺协会风险分层系统的比较研究在印度的患有差异化甲状腺癌的患者中

Malavika Satheesh¹, Malini Eapen², Usha V Menon³

¹Department of General Pathology, Christian Medical College, Vellore, Tamil Nadu, India.

Indian journal of endocrinology and metabolism

|November 13, 2025

概括

2009年和2015年美国甲状腺协会对差异化甲状腺癌 (DTC) 的风险分层系统 (ATA RSS) 显示了类似的结果. 较旧的ATA RSS-2009适合在资源有限的环境中进行初始风险分层.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
病理学病理学病理学

背景情况:

差异化甲状腺癌 (DTC) 风险分层对于患者管理至关重要.
美国甲状腺协会 (ATA) 风险分层系统 (RSS) 准则 (2009年和2015年) 用于预测复发性/持续性疾病 (RD/PD).
资源有限的环境可能会面临新的指导方针所要求的详细的组织病理学挑战.

研究的目的:

为了比较ATA RSS 2009年和2015年的DTC患者预测结果.
评估指南修订对风险状况重新分配的影响.
评估ATA RSS 2009在资源贫困环境中的实用性.

主要方法:

分析了221名成人DTC患者的队列,这些患者接受了全甲状腺切除和放射性切除.
使用临床病理参数根据ATA RSS 2009和2015重新分配风险类别.
两种系统之间的临床终点,包括对治疗的反应和最终结果,进行了比较.

主要成果:

根据ATA RSS 2015的重新分类导致风险状况与ATA RSS 2009中级类别相比变化很小 (9.4%).
一年后对治疗的反应和最终结果在类似的风险类别中是可比的,无论使用的ATA系统如何.
2009年和2015年的ATA RSS都在预测患者结果方面表现出类似的有效性.

结论:

与2009年ATA RSS相比,ATA RSS 2015没有显著改变风险分层.
ATA RSS 2009仍然是对DTC患者初始风险分层的可靠工具,特别是在资源有限的环境中.
这些发现支持在没有详细的遗传病理学数据的情况下继续使用ATA RSS 2009.

关键词:

ATA 2009 年风险分层系统.ATA风险分层系统2015年 ATA风险分层系统2015年印度印度印度有差异化的甲状腺癌.

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