在患有严重肺的患者中,评估分阶段与同时双边肺体积减小手术的有效性
Bryan F Vaca-Cartagena1, Alejandra Yu Lee-Mateus1, Sebastian Fernandez-Bussy1
1Division of Pulmonary, Allergy, and Sleep Medicine, Mayo Clinic, Jacksonville, FL, USA.
Journal of thoracic disease
|November 13, 2025
概括
阶段性肺体积减小手术 (LVRS) 的安全性和有效性与同时进行的双边LVRS相提并论,其5年复合生存结果明显更好.
科学领域:
- 肺部医学 肺部医学
- 胸部外科手术 胸部外科手术
- 关键护理医学 关键护理医学
背景情况:
- 肺体积减小手术 (LVRS) 是严重肺气的关键治疗方法.
- 双边LVRS通常比单边方法更受青.
- 有限的数据存在,比较分阶段与同时双边LVRS结果.
研究的目的:
- 评估分阶段与同时双边LVRS的安全性和有效性.
- 为了比较两种手术方法之间的并发症率,住院时间和长期存活率.
主要方法:
- 对接受LVRS.的81名严重肺气患者进行了回顾性队列研究.
- 术前和术后的肺功能测试的比较.
- 使用整体和无移植生存的复合结果的生存分析.
主要成果:
- 阶段性LVRS显示出明显更好的5年复合结果 (90.0%vs82.8%).
- 住院时间和肺炎和长时间空气泄漏的发病率在各组之间是相似的.
- 在分阶段治疗组中,皮下肺气的发生频率更高 (33%对12%).
- 这两种方法都显著改善了肺功能测试.
结论:
- 阶段性LVRS是同时双边LVRS的安全有效替代方案.
- 阶段式方法提供了优越的长期生存效益.
- 这两种方法都在肺瘤患者的肺功能上取得了显著的改善.
更多相关视频
09:31Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
2.5K
05:39Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
2.2K
相关概念视频
Flail Chest-II
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
Pneumothorax-II
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Atelectasis II: Pathophysiology
Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
