全球趋势和肺结核中的瘤亡因子-α的热点:一个图书计量和可视化分析
Min Xu1, Jiahui He2, Jianju Feng3
1Department of Respiratory and Critical Care Medicine, Zhuji People's Hospital of Zhejiang Province, Zhuji Affiliated Hospital of Wenzhou Medical University, Zhuji, China.
Journal of thoracic disease
|November 13, 2025
概括
这项研究分析了肺结核中瘤亡因子-α (TNF-α) 的全球研究. 研究结果显示,人们越来越关注生物标志物和炎症,转向诊断和个性化治疗.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 图书统计学 图书统计学
背景情况:
- 瘤亡因子-α (TNF-α) 在肺结核中起着双重作用,影响免疫力和组织损伤.
- 对TNF-α在结核病中的作用的研究兴趣正在增加,但缺乏全面的文献计量分析.
研究的目的:
- 对肺结核中TNF-α的全球研究趋势进行文献计量分析.
- 确定新兴的研究热点和该领域的关键贡献者.
主要方法:
- 从科学网络核心集合 (1990-2024) 中检索文献.
- 使用VOSviewer,CiteSpace和R 4.3.3.3 的图书统计分析.
- 对出版趋势,主要机构,作者,期刊和关键词的分析.
主要成果:
- 发表了1200篇文章,年增长率为10.73%.
- 美国在出版物和引用方面领先;印度医学研究委员会是最具生产力的机构.
- 诸如"mycobacterium-tuberculosis"",感染"",生物标志物"和"炎症"等关键词占据了突出位置,表明了对诊断的转变.
结论:
- 对肺结核TNF-α的研究正在从免疫机制发展到诊断和生物标志物.
- 未来的研究应该专注于验证TNF-α标记物,了解分子机制,并优化个性化治疗.
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