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Updated: Jan 11, 2026

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酸作为一种新的胆汁衍生生物标志物,用于与代谢功能障碍相关的脂肪性肝病

Soo Hyeon Lee1, Jonghwan Kim2, Sung Ryol Lee3

  • 1Department of Translational Medicine, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Republic of Korea.

Frontiers in endocrinology
|November 13, 2025
PubMed
概括

与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者表现出胆汁代谢物增加,包括酸,与纤维化严重程度相关. 基非酸盐激活GPR119受体可能会影响GLP-1的表达,这表明它是一个潜在的抗纤维素标.

关键词:
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In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
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