银纳米颗粒的绿色合成使用微波和传统方法:表征,抗癌和抗菌活动
Melek Hinis1, Tuğçe Karaduman Yeşildal2, Demet Erdönmez3
1Scientific and Technological Application and Research Centre, Aksaray University, Aksaray, Turkiye.
Turkish journal of chemistry
|November 13, 2025
概括
通过微波辅助 (MWA) 和传统方法 (TDM) 使用取物合成银纳米粒子 (Ag-NPs) 的绿色合成表明MWA更快,更经济. 合成的Ag-NP表现出显著的抗微生物和选择性抗癌活性.
科学领域:
- 纳米技术 纳米技术
- 绿色化学 绿色化学
- 材料科学 材料科学 材料科学
背景情况:
- 银纳米粒子 (Ag-NPs) 具有显著的生物活动.
- 开发对Ag-NPs的环保合成方法至关重要.
- 果果提取物为纳米粒子合成提供了一个可持续的来源.
研究的目的:
- 为了比较微波辅助 (MWA) 和传统的 (TDM) 绿色合成方法,使用苏马克提取物进行Ag-NPs.
- 描述合成的Ag-NP,并评估它们的抗微生物和抗癌特性.
- 评估两种合成方法的效率和经济可行性.
主要方法:
- 通过MWA和TDM使用果提取物合成Ag-NP的绿色合成.
- 使用UV-Vis光谱学,SEM/EDX和TEM进行表征.
- 对抗菌和抗真菌活动的评估.
- 对HT-29和L929细胞的细胞毒性评估.
主要成果:
- 无论是MWA和TDM方法都产生了高含银的球形Ag-NP.
- 与TDM (22 nm) 相比,MWA方法更快,更有效,产生更均分散的纳米粒子 (41.85 nm).
- 合成的Ag-NP显示出显著的抗菌,抗真菌和选择性抗癌作用,对肠癌细胞具有显著的抗菌,抗真菌和选择性抗癌作用,对正常细胞没有毒性.
结论:
- 与TDM相比,MWA方法是Ag-NPs的优越绿色合成方法,提供了更高的效率和经济效益.
- 来自 Sumac 的 Ag-NP 显示出治疗感染和肠道癌症的有希望的治疗潜力.
- 这项研究为优化双重生物应用的Ag-NPs的绿色合成参数提供了宝贵的见解.
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