格雷厄姆补丁与修改的格雷厄姆补丁在穿孔十二指肠的管理
Shahper Reza1, Md Arifur Rahman2, Zain Girach2
1Department of Surgery, Holy Family Red Crescent Medical College Hospital, Dhaka, BGD.
Cureus
|November 13, 2025
概括
这项研究发现,格雷厄姆贴片和修改的格雷厄姆贴片修复穿孔十二指肠之间的结果或并发症没有显著差异. 这两种手术技术在治疗十二指肠穿孔时都是安全有效的.
科学领域:
- 胃肠病学 胃肠病学
- 手术创新 在外科创新.
- 胃潰瘍疾病管理管理
背景情况:
- 穿孔十二指肠是一种关键的手术紧急情况.
- 迅速干预至关重要,以减少患者的死亡率和发病率.
- 手术修复技术旨在关闭穿孔并防止泄漏.
研究的目的:
- 为了比较格雷厄姆补丁与修改格雷厄姆补丁修复的有效性和安全性.
- 评估穿孔十二指肠患者的术后结果和并发症率.
- 评估修复技术对住院和康复的影响.
主要方法:
- 一项比较观察性研究,涉及60名患有十二指肠穿孔的患者.
- 患者被分为两组:格雷厄姆补丁修复 (30名患者) 和修改格雷厄姆补丁修复 (30名患者).
- 收集和分析了手术后并发症 (泄漏,伤口感染,发烧) 和住院的数据.
主要成果:
- 两组之间没有观察到伤口感染 (p=0.59) 或术后发烧 (p=0.78) 的统计学上显著差异.
- 平均住院时间相似:格雷厄姆贴片6天,修改格雷厄姆贴片8天 (p=0.145).
- 虽然90%的格雷厄姆贴片组有腹膜内,但67%的修饰组有,这表明在手术内发现的潜在差异.
结论:
- 传统和改性格雷厄姆补丁修复对于穿孔的十二指肠是安全有效的.
- 选择的技术可能取决于外科医生的经验和手术期间的条件.
- 建议进行较大的多中心试验,以证实长期结果,因为研究的局限性.
相关概念视频
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
798
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
798
01:26Peptic Ulcer Disease IV: Management
419
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
419
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
522
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
522
01:23Gastritis III: Clinical Manifestations and Management
1.1K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.1K
01:24Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
1.3K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
1.3K
01:21Inflammatory Bowel Disease V: Surgical Management
430
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
430