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在低氧条件下,FGF2支持NANOG表达,通过依赖于酸盐脱酶的基因素乙化,在低氧条件下支持NANOG表达

Petr Fojtík1,2,3, Martin Senfluk1, Katerina Holomkova1

  • 1Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Frontiers in cell and developmental biology
|November 13, 2025
PubMed
概括

酸盐脱酶 (PDH) 作为一种代谢开关,控制人体多能干细胞 (hPSC) 中的基因组乙化和多能性. 这个过程受到氧气水平和信号通路的调节,影响干细胞应用.

关键词:
在FGF2上.ROS - 活性氧物种 - 活性氧物种.基因素乙化 基因素乙化 基因素乙化这是一个纳米物质.多能性的多能性.酸盐脱酶 - - PDH - - 是一种

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