已出版的多发性硬化症护理国际指南的质量和范围:AGREE II评估
Sarah J Donkers1, Maya Berscheid1, Mark Bayley2,3
1College of Medicine, University of Saskatchewan, Saskatoon, Canada.
NeuroRehabilitation
|November 13, 2025
概括
现有的多发性硬化症 (MS) 临床实践指南 (CPG) 具有明确的目标,但缺乏实际应用和开发严格性. 需要一个全面的,更新的MS CPG与实施支持.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 临床实践指南 临床实践指南
背景情况:
- 对于多发性硬化症 (MS) 的康复和症状管理,目前还没有全面的临床实践指南 (CPG).
- 评估了现有的国际CPG,以告知未来全面指南的制定.
研究的目的:
- 系统地识别和评估现有的国际CPG的质量和范围.
- 评估当前MS CPG中的严谨性,清晰性,适用性和利益相关者参与度.
主要方法:
- 系统地搜索MS CPG电子数据库和灰色文献.
- 评估包括15个CPG,使用研究和评估指南评估II (AGREE-II) 工具,由4名独立审查员进行评估.
- 分析AGREE-II领域,并将建议组织成主题领域.
主要成果:
- 评估了来自美国,英国,加拿大和欧洲的15个CPG (1998-2020).
- 最高的AGREE-II分数是范围和目的 (83.2%) 和陈述清晰度 (79.6%).
- 最低的分数是适用性 (34.9%) 和开发严格性 (55.7%),其中12/15指南在适用性方面得分较低.
结论:
- 现有的MS CPG展示了明确的目标和目标人群.
- 然而,目前的指南在临床适用性和开发严格性方面存在局限性.
- 迫切需要一个全面的,最新的MS CPG,包括实施支持.
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