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Updated: Jan 6, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

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在高级不匹配的修复缺陷/微卫星不稳定性高的非结肠直肠癌中,尼沃卢马布和伊皮利马布:非随机临床试验

Matteo S Carlino1,2, Bo Gao1, Michael Michael3

  • 1Department of Medical Oncology, Blacktown and Westmead Hospitals, Sydney, Australia.

JAMA oncology
|November 13, 2025
PubMed
概括

与尼沃卢马布和伊皮利穆马布的联合免疫疗法在不匹配修复缺陷 (dMMR) /微卫星不稳定性高 (MSI-H) 的非结肠直肠癌中显示出高响应率. 这种方法提供了持久的反应,并可能是对这些罕见的免疫性瘤单一治疗的有价值的替代方案.

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