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Updated: Jan 11, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
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A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

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原始体效应和独特的转录基因特征与克隆扩展的抗原特异性CD8 T记忆干细胞中的分化表型相关

Yanran Zhao1,2, Jerome Samir2, Elizabeth Keoshkerian1,2

  • 1Viral Immunology Systems Program, The Kirby Institute, University of New South Wales, Sydney, Australia.

Journal of immunology (Baltimore, Md. : 1950)
|November 13, 2025
PubMed
概括

记忆干CD8+T细胞 (TSCM) 对抗病毒免疫非常重要. 这项研究表明,TSCM后代保留了祖先的特征,TSCM细胞具有独特的基因特征,用于分化和功能,这对免疫疗法至关重要.

关键词:
在CD8 T细胞中,CD8 T细胞克隆血统的克隆血统是什么?遗传性 遗传性 遗传性这就是 scRNA-seqq.干细胞记忆T细胞T细胞

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Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays08:56

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