美国成年人中COVID-19疫苗接种和亚托皮性疾病之间的关联:一项回顾性队列研究
Min Lu1, Zixuan Bu2, Nana Xiang3
1Department of Otolaryngology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China.
PloS one
|November 13, 2025
概括
接种COVID-19疫苗与成年人患花粉热的风险更高有关,但与皮肤,喘或食物过敏的风险增加无关. 需要进一步的研究来理解这些关联.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- COVID-19疫苗对过敏反应的影响需要进一步调查.
- 关于COVID-19疫苗接种与亚托皮性疾病之间存在关联的证据有限.
研究的目的:
- 为了检查COVID-19疫苗接种与成人亚托皮性疾病风险之间的关联.
- 为了确定COVID-19疫苗接种是否会增加花粉热,喘,皮肤过敏和食物过敏的发生率.
主要方法:
- 使用2021年美国国家卫生访谈调查 (NHIS) 数据进行的横截面调查.
- 包括29,201名18岁及以上的成年人.
- 多变量逻辑回归分析以估计赔率比率 (aOR) 和95%置信区间 (CI).
主要成果:
- 接种COVID-19疫苗与更高的花粉热几率显著相关 (aOR,1.21;P < 0.001).
- 在COVID-19疫苗接种和皮肤过敏,喘或食物过敏风险增加之间没有发现显著的关联.
- 接种COVID-19疫苗剂量的数量与新诊断的花粉热和喘有关.
结论:
- 接种COVID-19疫苗与花粉热发病率的增加有关.
- COVID-19疫苗接种似乎没有增加皮肤过敏,喘或食物过敏的发病风险.
- 未来的研究应该确定COVID-19疫苗接种和亚托皮性疾病之间的关联的决定因素.
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