多元组件癌症疼痛认知行为疗法的试点测试 mHealth 应用程序用于晚期癌症患者.
Desiree R Azizoddin1,2, Sara M DeForge1, Jian Zhao1
1Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences, Oklahoma City, OK.
JCO clinical cancer informatics
|November 13, 2025
概括
对于晚期癌症患者来说,将疼痛认知行为疗法 (疼痛-CBT) 与阿片类药物管理相结合的移动健康干预是可行的和可以接受的. 虽然从统计学上没有显著意义,但定性数据显示疼痛自我管理知识和应对技能的改善.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 疼痛管理 疼痛管理
背景情况:
- 晚期癌症患者经常经历疼痛,需要有效的管理策略.
- 疼痛认知行为疗法 (疼痛-CBT) 是有效的,但面临着访问限制.
- 移动健康 (mHealth) 提供了一种潜在的解决方案,以改善获得疼痛管理干预措施的机会.
研究的目的:
- 评估针对晚期癌症疼痛的移动健康干预措施的可行性和可接受性.
- 这项干预将疼痛-CBT与阿片类药物教育和跟踪相结合.
- 目标是改善晚期癌症患者的慢性疼痛管理.
主要方法:
- 一个为期28天的基于智能手机的干预措施在使用阿片类药物的高级癌症和显著疼痛的成年人中进行了测试.
- 可行性被定义为应用程序使用率≥50%,可接受性用E级测量.
- 干预评估了疼痛,情绪,灾难化,睡眠和阿片类药物使用,提供了适应性干预和精神教育.
- 进行了前后调查和定性访谈,以评估结果和患者体验.
主要成果:
- 招募了32名患者,59%的患者达到≥50%的应用使用可行性门.
- 这项干预措施表现出良好的可接受性 (E级平均得分:24.85).
- 在4周和6周的随访期间,没有观察到疼痛强度,干扰或灾难性的统计显著减少.
- 定性访谈显示增加了疼痛自我管理知识,增强了应对技巧,并减少了阿片类药物污名.
结论:
- 对于患有晚期癌症疼痛的患者来说,mHealth疼痛-CBT干预是可行的和可以接受的.
- 探索性分析没有显示疼痛结果的显著改善.
- 定性发现表明有意义的患者参与和技能发展,保证进一步的疗效测试.
相关概念视频
Cancer Therapies
9.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.8K
Combination Therapies and Personalized Medicine
5.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.9K
Treatment Resistant Cancers
3.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K


