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波马利多米德增强了CD8+ T和NK细胞介导的杀死HIV感染细胞的作用

Rachel D Pascoe1, Celine Gubser2, J Judy Chang2

  • 1Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, 3000, Australia.

EBioMedicine
|November 13, 2025
PubMed
概括

在接受抗逆转录病毒疗法 (ART) 的艾滋病毒感染者 (PLHIV) 中,波马利多米德增强了免疫反应. 这种免疫调节药物扩大了HIV特异性T细胞和自然杀手 (NK) 细胞,提高了它们对抗HIV的能力,以寻求潜在的治疗策略.

关键词:
CD8 ((+) T 细胞消耗 耗尽 已经 耗尽 已经 耗尽人类免疫缺陷病毒 (HIV)免疫调节是一种免疫调节.在 NK 细胞中,NK 细胞是 NK 细胞.

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