解读腺菌和微生物群之间的关系:一个系统性审查
Çağlayan Ateş1, Berna Dilbaz2, Koray Görkem Saçıntı3
1Department of Obstetrics and Gynecology, Yozgat Bozok University Faculty of Medicine, 66100 Yozgat, Turkey.
European journal of obstetrics, gynecology, and reproductive biology
|November 13, 2025
概括
这一系统性审查将特定的细菌与腺菌症联系起来,这是一种涉及子宫组织移位的疾病. 研究强调了腺菌症患者子宫内膜,阴道和肠道微生物组的变化,但因果关系尚不清楚.
科学领域:
- 妇科病理学的病理学
- 微生物组研究的研究.
- 生殖医学是一种生殖医学.
背景情况:
- 人们还没有完全理解腺菌病原体.
- 新兴的研究表明,微生物群失生症和腺菌症之间存在联系.
- 微生物群和腺菌症之间的相互作用的确切性质需要进一步阐明.
研究的目的:
- 系统地审查现有的关于微生物群和腺菌病之间的关系的文献.
- 为了识别与腺菌症相关的特定微生物变化.
- 探索子宫内膜,阴道和肠道微生物在腺菌症中的作用.
主要方法:
- 在PubMed,Scopus,Google Scholar和Web of Science的系统文献搜索,直到2024年6月.
- 包括7项研究 (6人,1只动物),涉及670名人类和16只小鼠.
- 来自子宫内膜,阴道和肠道样本的微生物组数据的分析,主要使用16S rRNA基因测序.
主要成果:
- 增加了Firmicutes,Rhodospirillales,Ruminococcus gauvreauii,Citrobacter freundii,Prevotella copri,Burkholderia cepacia的丰富性,以及在腺菌中CST-III和CST-IV的占主导地位.
- 减少了Clostridiacea,Peptostreptococcaceae,Atopobiacea家族和Fastidiosipila,Magasphaera sp.种类的丰富性 在腺菌症中的物种.
- 在不同的身体部位识别与腺菌相关的不同细菌物种.
结论:
- 本综述强调了与腺肌症相关的特定细菌特征.
- 在腺菌症中观察到女性生殖道和肠道微生物群的显著变化.
- 需要进一步的研究来确定这些微生物变化是否是导致或导致腺菌症.
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