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Updated: Jan 11, 2026

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
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肠道的隐藏武器库:II类细菌菌素的基因组学指导的地图

Tianang Leng1, Cesar de la Fuente-Nunez1

  • 1Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA.

Cell genomics
|November 13, 2025
PubMed
概括

研究人员开发了IIBacFinder,以发现新型II类细菌素,即精密抗菌剂. 合成的细菌素显示出有效性,并挽救了肠道微生物,为传统抗生素提供了有希望的替代品.

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