结核病后的肺病:用于研究研究中的病例定义
Gregory P Bisson1, Brian Allwood2, Anthony Byrne3
1Department of Medicine, Division of Infectious Diseases, Perelmen School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Biostatistics, Epidemiology, and Informatics, Division of Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
结核后肺病 (PTLD) 的新病例定义旨在标准化研究. 这一定义将提高对PTLD的研究的一致性,使全球结核病幸存者受益.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 长期肺功能障碍是结核病幸存者的重要问题.
- 定义肺结核后肺病 (PTLD) 的变化阻碍了研究综合.
研究的目的:
- 为研究研究提出PTLD的标准化案例定义.
- 促进PTLD研究的协调和一致性.
主要方法:
- 在第二届国际结核病后研讨会上通过利益相关者的意见开发.
- 根据指导原则进行精炼:具体性,可行性,结果相关性和适用性.
- 包含三个组成部分:先前的结核病,当前的肺病证据和先前结核病的归因.
主要成果:
- 提出了一个为PTLD提出的三组件案例定义.
- 提供了一个补充报告框架.
结论:
- 拟议的定义旨在提高PTLD研究的一致性和严格性.
- 这种标准化旨在改善全球结核病幸存者的护理和生活质量.
- 该定义是为研究用途而设计的,并可能随着新的证据而演变.
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