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中和IL-22RA1改善了与阿托皮性皮炎病原发生相关的组织学和分子变化

Sophia Wasserer1, Thomas Litman2, Josephine Hebsgaard2

  • 1Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.

The Journal of allergy and clinical immunology
|November 13, 2025
PubMed
概括

阻断IL-22/IL-22受体 (IL-22RA1) 轴显示了对亚托皮炎 (AD) 的治疗潜力. 这项研究发现IL-22RA1有助于AD的发病,其抑制改善了模型中的皮肤屏障完整性.

关键词:
亚托邦性皮肤炎 (Atopic Dermatitis) 是一种不良的疾病.在IL-22中,我们可以看到IL-22.这是一种 IL-22RA1 蛋白.皮肤炎症 皮肤炎症这就是Temtokibart.治疗治疗治疗治疗治疗治疗

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