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Updated: Jan 11, 2026

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对陶病的实验建模:一个同位素面板的人性化MAPT敲进小鼠

Takahiro Morito1, Naoto Watamura2

  • 1RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

Neuroscience research
|November 13, 2025
PubMed
概括

新的MAPT敲入 (KI) 鼠标模型在本地促成者控制下表达人类tau突变. 这些模型为研究病症和开发神经退行性疾病治疗方法提供了更生理的方法.

关键词:
基因组编辑 基因组编辑马普特敲门式的入口鼠标模型的模型神经退行发生神经退行.陶氏病变 (tauopathies) 是一种疾病.

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