流行病学,关联和急性排泄性多态形黄斑病变 (AEPVM) 的治疗
Tobin Smith1, Vivian Rajeswaren1, Brittany Hodges1
1Department of Ophthalmology Visual & Anatomical Sciences, Kresge Eye Institute, Wayne State University School of Medicine, Detroit, MI, USA.
Seminars in ophthalmology
|November 13, 2025
概括
急性排泄性多态维特利型黄斑病变 (AEPVM) 可能与黑色素瘤有关. 了解AEPVM的原因和治疗对于患者的管理和早期黑色素瘤检测至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 医学研究 医学研究
背景情况:
- 急性排泄性多形维特利状黄斑病 (AEPVM) 是一种罕见的视网膜疾病.
- 它呈现出血清性子皮脱落和形病变.
研究的目的:
- 审查目前关于AEPVM病因和治疗方法的知识.
- 探索AEPVM与黑色素瘤之间的关联.
主要方法:
- 在PubMed,MEDLINE和Embase的综合文献搜索到2025年3月.
- 分析了81个已确定的AEPVM病例.
主要成果:
- 确定的病因:异常病 (43),传染病 (10),瘤病 (19),药物诱导的 (9).
- 皮质类固醇改善了异常,传染病和药物诱导的AEPVM的结果.
- 麻性AEPVM对免疫疗法,化疗,甲状腺素和aflibercept的反应有所不同.
- 在5例病例中,AEPVM先于原发性或转移性黑色素瘤.
结论:
- 可变的治疗反应需要进一步的研究.
- 识别AEPVM对于迅速诊断黑色素瘤和其他相关疾病至关重要.
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