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Updated: Jan 11, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
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亨廷顿病:人体扩张,病理生物学和治疗方法

Jasmine Donaldson1,2, Davina Hensman Moss1,2, Marc Ciosi3

  • 1Huntington's Disease Centre and Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.

Nature reviews. Neurology
|November 13, 2025
PubMed
概括

DNA重复的体质扩张,就像亨廷顿病中的CAG重复一样,驱动神经退行. 准DNA修复途径可能为这些遗传性疾病提供新的治疗策略.

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