相关实验视频

Updated: Aug 6, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

11.8K

细胞表面蛋白CD47和TRP1由谷氨基基环酶的黄化调节治疗性抗体结合

Anneloes van der Plas-van Duijn1,2, Levi M T Winkelman3, Claire Lensen1

  • 1Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.

Communications biology
|November 13, 2025
PubMed
概括

蛋白质修饰的 Pyroglutamation 影响治疗性抗体与癌症点 CD47 和 TRP1.1 结合. 这种修改影响抗体亲和力和蛋白质贩运,突出其在基于抗体的癌症治疗中的作用.

更多相关视频

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques08:58

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques

Published on: July 5, 2018

13.1K
Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction11:02

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Published on: September 14, 2018

8.1K

相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.