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Updated: Jan 11, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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全基因组关联分析确定了早期和晚期抑郁症的独特遗传架构

John R Shorter1, Joëlle A Pasman2,3, Siim Kurvits4

  • 1Department of Science and Environment, Roskilde University, Roskilde, Denmark. johnsh@ruc.dk.

Nature genetics
|November 13, 2025
PubMed
概括

早期出现的大型抑郁症 (MDD) 和晚期出现的MDD具有不同的遗传基础. 早期发病的MDD遗传风险得分预测了自杀企图,为抑郁症提供了精确精神病学信息.

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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

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