相关实验视频

Updated: Jul 15, 2026

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells
12:06

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells

Published on: January 11, 2019

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一个原始的生殖细胞类细胞平台使CRISPRi能够选表观遗传生育修饰剂

Liangdao Li1, Jingyi Gao1, Dain Yi1

  • 1Cornell University, College of Veterinary Medicine, Department of Biomedical Sciences, Ithaca, NY, 14853, USA.

EMBO reports
|November 13, 2025
PubMed
概括

研究人员开发了一种可扩展的方法,通过过度表达关键基因,从干细胞中产生丰富的原始生殖细胞样细胞 (PGCLC). 这一突破使得对生殖线发育至关重要的表观遗传因素的大规模功能查成为可能.

关键词:
克里斯普里是指克里斯普里.表观基因组是一个表观基因组.生育能力 生育能力 生育能力阻断了基脱乙酶的抑制作用.在PGCLCs中,PGCLCs是最重要的.

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